Jacksonville Jaguars rout Indianapolis Professional Football Team 42-7; Hamilton injured
JACKSONVILLE — The Jacksonville Jaguars routed the Indianapolis Professional Football Team 42-7 at EverBank Stadium on Sunday, Nov. 1, 2026. The game was played on Nov. 1, 2026. The victory came with a significant loss when veteran nose tackle DaVon Hamilton exited with a knee injury early in the second quarter, and starters were pulled late after the outcome was decided.
The account and game details were reported by John Oehser, Brian Sexton, Kainani Stevens and John Shipley on Nov. 1, 2026. John Shipley wrote that Trevor Lawrence threw three touchdown passes and had four incompletions. The Jaguars established a physical running game, including a 39-yard, tackle-breaking run by second-year running back Bhayshul Tuten that set up a 21-0 lead late in the first half. Running back Chris Rodriguez Jr. added a 28-yard touchdown run early in the third quarter that extended the lead to 35-0.
Jacksonville’s defense received several game-changing plays from depth players, the reports said. Second-year safety Rayuan Lane III returned an interception 92 yards for a touchdown with 10 seconds remaining in the first half. Linebacker Branson Combs recorded his first career interception and made impact plays on special teams, and undrafted rookie defensive end Bryan Thomas Jr. recovered a first-half fumble that led to a scoring drive. Those contributions allowed the Jaguars to sustain pressure despite some in-game injuries.
The victory left the Jaguars with a three-game lead in the AFC South as October turned into November, the reports said. It came against an Indianapolis Professional Football Team that had traded away All-Pro guard Quenton Nelson and All-Pro defensive tackle DeForest Buckner during the prior week. Jaguars coach Liam Coen said, “The guys came in with a little blood in the water and we wanted to be able to jump on these guys at home.” Coen added that Hamilton was one of the team’s best competitors and that Hamilton was ruled out for the game after leaving on a cart with a knee injury.
NFL Sports Blog Take
The Jaguars showed depth and dominance in a one-sided win that reinforced their standing atop the AFC South, but DaVon Hamilton’s knee injury presents a significant concern for a run defense that has been a cornerstone of the team’s success. Backup players stepped up in key moments, which will matter if Hamilton misses extended time. Resting starters late is valuable with a short week ahead and a Thursday trip to Baltimore, and the team will await further medical updates in the days to come.